胡瓊政,,博士,研究員,,山東省泰山學(xué)者青年專家,,齊魯工業(yè)大學(xué)(山東省科學(xué)院)生化傳感和藥物分析團(tuán)隊(duì)課題組組長(zhǎng)。先后在美國(guó)華盛頓大學(xué),、索爾克生物研究所,、休斯頓大學(xué)、韓國(guó)嘉泉大學(xué)和山東大學(xué)從事生化傳感和藥物分析方面的研究,,在生物傳感、藥物分析,、微流控和微生物等研究領(lǐng)域積累了豐富的經(jīng)驗(yàn),。先后主持和參與多項(xiàng)國(guó)家和省部級(jí)研究課題,,發(fā)表包括Angew. Chem. Int. Ed., Proc. Natl. Acad. Sci. U.S.A, Anal. Chem., Biosens. Bioelectron., Chem. Commun. 等SCI論文40余篇,其中第一作者和通訊作者論文20余篇,,授權(quán)專利2項(xiàng)(美國(guó)和歐洲專利各1項(xiàng)),,長(zhǎng)期擔(dān)任Chem. Commun., Theranostics, Sens. Actuators. B Chem., Talanta, Food Chem.等多個(gè)國(guó)內(nèi)外知名期刊的評(píng)審專家。
課題組常年招聘優(yōu)秀博士(特聘副教授,、助理研究員)和博士后,;同時(shí)招收化學(xué)和化工專業(yè)的碩士生。歡迎感興趣的同學(xué)聯(lián)系和報(bào)考,。課題組主頁(yè):https://www.x-mol.com/groups/HuLab,;郵箱:[email protected]。
研究興趣和領(lǐng)域:
1. 生物傳感,;
2. 藥物分析,;
3. 微流控;
4. 微生物,。
主要發(fā)表論文:
1. Lubin Qi, Shuya Liu, Yifei Jiang, Jin-Ming Lin, Li Yu*, Qiongzheng Hu*. Simultaneous detection of multiple tumor markers in blood by functional liquid crystal sensors assisted with target-induced dissociation of aptamer. Analytical Chemistry, 2020. DOI: 10.1021/acs.analchem.9b05317.
2. Lubin Qi, Qiongzheng Hu*, Qi Kang, Yanhui Bi, Yifei Jiang, Li Yu*. Detection of biomarkers in blood using liquid crystals assisted with aptamer-target recognition triggered in situ rolling circle amplification on magnetic beads. Analytical Chemistry, 2019, 91, 11653-11660.
3. Huizhong Xu, Zhisong Tong, Qing Ye, Tengqian Sun, Zhenmin Hong, Lunfeng Zhang, Alexandra Bortnick, Sunglim Cho, Paolo Beuzer, Joshua Axelrod, Qiongzheng Hu, Melissa Wang, Sylvia M. Evans, Cornelis Murre, Li-Fan Lu, Sha Sun, Kevin D. Corbett, and Hu Cang*. Molecular organization of mammalian meiotic chromosome axis revealed by expansion STORM microscopy. Proceedings of the National Academy of Sciences, 2019, 116, 18423-18428.
4. Lubin Qi+, Qiongzheng Hu+, Qi Kang, Li Yu*. Fabrication of liquid-crystal-based optical sensing platform for detection of hydrogen peroxide and blood glucose. Analytical Chemistry, 2018, 90, 11607-11613. (Co-first author)
5. Qiongzheng Hu, Haopeng Yang, Yuhong Wang, Shoujun Xu*. Quantitatively resolving multivalent interactions on a macroscopic scale using force spectroscopy. Chemical Communications, 2016, 52, 3705-3708.
6. Qiongzheng Hu, Shoujun Xu*. Sequence and chiral selectivity of drug–DNA interactions revealed by force spectroscopy. Angewandte Chemie International Edition, 2014, 53, 14135-14138.
7. Yi Wang+, Qiongzheng Hu+, Yongxian Guo, Li Yu*. A cationic surfactant-decorated liquid crystal sensing platform for simple and sensitive detection of acetylcholinesterase and its inhibitor. Biosensors and Bioelectronics, 2015, 72, 25-30. (Co-first author)
8. Tongtong Tian+, Qiongzheng Hu+, Yi Wang, Ya-Nan Gao, Li Yu*. Reversible photoresponsive molecular alignment of liquid crystals at fluid interfaces with persistent stability. Chemistry – A European Journal, 2016, 22, 6340-6344. (Co-first author)
9. Lele Zhou+, Qiongzheng Hu+, Qi Kang, Ming Fang, Li Yu*. Construction of a liquid crystal-based sensing platform for sensitive and selective detection of L-phenylalanine based on alkaline phosphatase. Langmuir, 2018, 35, 461-467. (Co-first author)
10. Yanjun Gong+, Qiongzheng Hu+, Chen Wang, Ling Zang, Li Yu*. Stimuli-responsive polyoxometalate/ionic liquid supramolecular spheres: fabrication, characterization, and biological applications. Langmuir, 2016, 32, 421-427. (Co-first author)
11. Qiongzheng Hu, ChangHyun Jang*. Real-time and sensitive detection of lipase using liquid crystal droplet patterns supported on solid surfaces. Liquid Crystals, 2014, 41, 597-602.
12. Qiongzheng Hu, ChangHyun Jang*. Spontaneous formation of micrometer-scale liquid crystal droplet patterns on solid surfaces and their sensing applications. Soft Matter, 2013, 9, 5779-5784.
13. Qiongzheng Hu, Hyunkyung Shin, ChangHyun Jang*. Dynamic imaging of enzymatic events at polyelectrolyte-disrupted phospholipid membranes using liquid crystals. Liquid Crystals, 2013, 40, 106-111.
14. Qiongzheng Hu, Chang-Hyun Jang*. Imaging trypsin activity through changes in the orientation of liquid crystals coupled to the interactions between a polyelectrolyte and a phospholipid layer. ACS Applied Materials & Interfaces, 2012, 4, 1791-1795.
15. Qiongzheng Hu, ChangHyun Jang*. A new strategy for imaging biomolecular events through interactions between liquid crystals and oil-in-water emulsions. Analyst, 2012, 137, 5204-5207.
16. Qiongzheng Hu, ChangHyun Jang*. A simple strategy to monitor lipase activity using liquid crystal-based sensors. Talanta, 2012, 99, 36-39.
17. Qiongzheng Hu, ChangHyun Jang*. Using liquid crystals for the label-free detection of catalase at aqueous–LC interfaces. Journal of Biotechnology, 2012, 157, 223-227.
18. Qiongzheng Hu, ChangHyun Jang*. Using liquid crystals for the real-time detection of urease at aqueous/liquid crystal interfaces. Journal of Materials Science, 2012, 47, 969-975.
19. Qiongzheng Hu, ChangHyun Jang*. Orientational behaviour of ultraviolet-tailored 4-cyano-4'-pentylbiphenyl at the aqueous/liquid crystal interface. Liquid Crystals, 2011, 38, 1209-1216.
20. Qiongzheng Hu, ChangHyun Jang*. Liquid crystal-based sensors for the detection of heavy metals using surface-immobilized urease. Colloids and Surfaces B: Biointerfaces, 2011, 88, 622-626.